发明授权
- 专利标题： Thioformamide derivatives
- 专利标题（中）： 硫代甲酰胺衍生物
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申请号： US531335申请日： 1995-09-20
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公开(公告)号： US5606061A公开(公告)日： 1997-02-25
- 发明人: Yasuhiro Kabasawa , Fumihiro Ozaki , Keiji Ishibashi , Takashi Hasegawa , Hitoshi Oinuma , Toshiaki Ogawa , Hideyuki Adachi , Hiroshi Katoh , Kohtarou Kodama , Hideto Ohara , Nobuyuki Mori , Norio Minami
- 申请人： Yasuhiro Kabasawa , Fumihiro Ozaki , Keiji Ishibashi , Takashi Hasegawa , Hitoshi Oinuma , Toshiaki Ogawa , Hideyuki Adachi , Hiroshi Katoh , Kohtarou Kodama , Hideto Ohara , Nobuyuki Mori , Norio Minami
- 申请人地址： JPX
- 专利权人： Eisai Co., Ltd.
- 当前专利权人： Eisai Co., Ltd.
- 当前专利权人地址： JPX
- 优先权： JPX3-264622 19911014; JPX4-197 19920106
- 主分类号： C07D231/12
- IPC分类号： C07D231/12 ; C07D233/92 ; C07D233/95 ; C07D471/04
摘要：
The present invention provides a thioformamide derivative represented by the following general formula (I) or a pharmacologically acceptable salt thereof, which is highly safe, easy to use, and useful as an excellent hypotensive or heart disease remedy: ##STR1## wherein Y represents ##STR2## or the like [wherein R.sup.7 represents benzyloxy or the like; R.sup.11 and R.sup.12 each represent hydrogen, hydroxyl, benzoyloxy, benzyloxy, ##STR3## (wherein R.sup.14 and R.sup.15 each represent hydrogen, benzyl or the like) or the like];Z represents --CH.sub.2 -- or the like; A represents imidazolyl or imidazopyridyl which may have one or two substituents, or the like; R.sup.1 and R.sup.2 each represent hydrogen, lower alkyl or the like; and R.sup.3 and R.sup.4 each represent hydrogen, lower alkyl or the like.
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