发明授权
- 专利标题： Process for attenuated varicella zoster virus vaccine production
- 专利标题（中）： 减毒水痘带状疱疹病毒疫苗生产过程
-
申请号： US347345申请日： 1994-12-05
-
公开(公告)号： US5607852A公开(公告)日： 1997-03-04
- 发明人: Philip J. Provost , David L. Krah , Paul A. Friedman
- 申请人： Philip J. Provost , David L. Krah , Paul A. Friedman
- 申请人地址： NJ Rahway
- 专利权人： Merch & Co., Inc.
- 当前专利权人： Merch & Co., Inc.
- 当前专利权人地址： NJ Rahway
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/12 ; A61K39/25 ; A61P31/12 ; A61P31/22 ; C12N1/38 ; C12N5/00 ; C12N5/02 ; C12N5/071 ; C12N5/10 ; C12N7/04 ; C12N7/08 ; C12N9/84 ; C12N7/00 ; A61K39/245
摘要：
A live, attenuated varicella zoster virus vaccine is produced with enhanced yield of VZV. The new process makes mass production of a live VZV vaccine more practical. In addition, optimized monoloyer cell culture conditions provide a process for maximizing monolayer cell density which is useful for enhancing viral vaccine production. According to this process, cell densities approaching 500,000 cells/cm.sup.2 are routinely achieved in conventional culture vessels.
公开/授权文献
- US4960253A Compact lightweight wireway 公开/授权日：1990-10-02