发明授权
- 专利标题: Injectable drug delivery system and method
- 专利标题(中): 注射药物递送系统及方法
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申请号: US437471申请日: 1995-05-09
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公开(公告)号: US5620700A公开(公告)日: 1997-04-15
- 发明人: Randall G. Berggren , David J. Enscore , Susan M. Marks , James L. Osborne , Patrick S.-L. Wong , Wouter E. Roorda
- 申请人: Randall G. Berggren , David J. Enscore , Susan M. Marks , James L. Osborne , Patrick S.-L. Wong , Wouter E. Roorda
- 申请人地址: CA Palo Alto
- 专利权人: ALZA Corporation
- 当前专利权人: ALZA Corporation
- 当前专利权人地址: CA Palo Alto
- 主分类号: A61C19/06
- IPC分类号: A61C19/06 ; A61K6/00 ; A61K47/34
摘要:
The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days.
公开/授权文献
- US5066711A Wetness indicating hot-melt adhesives 公开/授权日:1991-11-19