利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

70 条记录 (耗时 0.043 秒)

    Injectable drug delivery system and method
    1.
    发明授权
    Injectable drug delivery system and method 失效
    注射药物递送系统及方法

    公开(公告)号：US5783205A

    公开(公告)日：1998-07-21

    申请号：US843682

    申请日：1997-04-10

    申请人： Randall G. Berggren ,  David J. Enscore ,  Susan M. Marks ,  James L. Osborne ,  Patrick S.-L. Wong ,  Wouter E. Roorda

    发明人： Randall G. Berggren ,  David J. Enscore ,  Susan M. Marks ,  James L. Osborne ,  Patrick S.-L. Wong ,  Wouter E. Roorda

    IPC分类号： A61C19/06 ,  A61K6/00 ,  A61K9/00 ,  A61K9/22 ,  A61K47/34 ,  A61F2/02

    CPC分类号： A61C19/063 ,  A61K6/0067 ,  A61K9/0063 ,  A61K47/34

    摘要： The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days.

    摘要翻译： 本发明涉及可用于将诸如抗生素的药物递送到患病组织袋（例如牙周袋）中的材料。 该材料优选为生物可腐蚀的低聚物或聚合物。 包含药物的低聚物或聚合物被加热，然后优选通过注射递送到生理上相容的升高的温度下的组织袋中。 一旦将生物可蚀解材料注入到口袋中，则该材料冷却到口袋的体温。 当它冷却时，材料硬化并保持在组织袋中的适当位置。 硬化的材料在口袋中传播并在几天的时间内释放药物。

    Injectable drug delivery system and method
    2.
    发明授权
    Injectable drug delivery system and method 失效
    注射药物递送系统及方法

    公开(公告)号：US5620700A

    公开(公告)日：1997-04-15

    申请号：US437471

    申请日：1995-05-09

    申请人： Randall G. Berggren ,  David J. Enscore ,  Susan M. Marks ,  James L. Osborne ,  Patrick S.-L. Wong ,  Wouter E. Roorda

    发明人： Randall G. Berggren ,  David J. Enscore ,  Susan M. Marks ,  James L. Osborne ,  Patrick S.-L. Wong ,  Wouter E. Roorda

    IPC分类号： A61C19/06 ,  A61K6/00 ,  A61K47/34

    CPC分类号： A61C19/063 ,  A61K47/34

    摘要： The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days.

    摘要翻译： 本发明涉及可用于将诸如抗生素的药物递送到患病组织袋（例如牙周袋）中的材料。 该材料优选为生物可腐蚀的低聚物或聚合物。 包含药物的低聚物或聚合物被加热，然后优选通过注射递送到生理上相容的升高的温度下的组织袋中。 一旦将生物可蚀解材料注入到口袋中，则该材料冷却到口袋的体温。 当它冷却时，材料硬化并保持在组织袋中的适当位置。 硬化的材料在口袋中传播并在几天的时间内释放药物。

    Drug delivery device with minimal residual drug retention
    7.
    发明授权
    Drug delivery device with minimal residual drug retention 失效
    具有最小残留药物保留率的药物输送装置

    公开(公告)号：US5902605A

    公开(公告)日：1999-05-11

    申请号：US851525

    申请日：1997-04-18

    申请人： Liang C. Dong ,  Patrick S.-L. Wong ,  Si-Hong Yum ,  Crystal Pollock

    发明人： Liang C. Dong ,  Patrick S.-L. Wong ,  Si-Hong Yum ,  Crystal Pollock

    IPC分类号： A61K9/00 ,  A61K9/22

    CPC分类号： A61K9/0004

    摘要： The present invention is directed to a fluid-imbibing drug delivery device which is useful for the initial delayed delivery of an active agent formulation to a fluid environment of use, the initial delay period to startup or activation of the device being of a predetermined length of time. The delivery of the agent formulation from the dispensing device is continued until essentially all of the active agent formulation is delivered as a result of the fluid inhibition into a fluid flow path in the housing of the device and the expansion of an expansion agent in the active agent delivery chamber.

    摘要翻译： 本发明涉及一种流体吸收药物递送装置，其可用于将活性剂制剂初始延迟递送至使用的流体环境，初始延迟时间为启动或启动装置的预定长度 时间。 药剂制剂从分配装置的输送继续进行，直到基本上所有的活性剂制剂由于液体抑制被输送到装置的壳体中的流体流动路径和活性物质中膨胀剂的膨胀而被递送 代理商送货室。

    Dispenser with movable matrix comprising a plurality of tiny pills
    10.
    发明授权
    Dispenser with movable matrix comprising a plurality of tiny pills 失效
    具有可移动矩阵的分配器，包括多个微小的药丸

    公开(公告)号：US4915949A

    公开(公告)日：1990-04-10

    申请号：US312270

    申请日：1989-02-21

    申请人： Patrick S.-L. Wong ,  Felix Theeuwes ,  Richard Cortese ,  James B. Eckenhoff

    发明人： Patrick S.-L. Wong ,  Felix Theeuwes ,  Richard Cortese ,  James B. Eckenhoff

    IPC分类号： A61K9/00 ,  A61K9/22

    CPC分类号： A61K9/0068 ,  A61K9/0004

    摘要： A dispenser is disclosed for delivering tiny pills to an environment of use. The dispenser comprising a wall that surrounds an internal space comprising a first mean in the dispenser for changing from a dispenser state to an environment of use state on leaving the dispenser, tiny pills in the first means, and a second means in the dispenser for aiding in displacing the first means for the dispenser.

    摘要翻译： 公开了用于将微小丸剂递送到使用环境的分配器。 所述分配器包括围绕内部空间的壁，所述壁包括所述分配器中的第一平均值，用于在离开所述分配器时从分配器状态改变为使用状态，所述第一装置中的小丸和用于辅助的所述分配器中的第二装置 在移动分配器的第一装置时。