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1.
公开(公告)号:US5713852A
公开(公告)日:1998-02-03
申请号:US475233
申请日:1995-06-07
CPC分类号: A61K9/0004
摘要: A method is described for delivering a beneficial agent, such as an antiinflammatory agent, to the site of a painful condition in the oral cavity of a human being that utilizes an oral dosage form having an immediately releasable topical anesthetic and a sustained release beneficial agent. The topical anesthetic is released substantially independently of the beneficial agent to provide immediate pain relief and the application of the beneficial agent is continued over a long period of time.
摘要翻译: 描述了一种用于将有益药物(例如抗炎剂)递送到使用具有立即可释放的局部麻醉剂和持续释放有益剂的口服剂型的人口腔中的疼痛状况的部位的方法。 局部麻醉剂基本上独立于有益药物释放,以立即缓解疼痛,并且长期持续有益药物的应用。
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公开(公告)号:US6124355A
公开(公告)日:2000-09-26
申请号:US78192
申请日:1998-05-13
IPC分类号: A61K9/00 , A61K9/20 , A61K31/216 , A61K31/221 , A01N37/44
CPC分类号: A61K9/0004 , A61K31/216 , A61K31/221 , A61K9/2031 , A61K9/2054
摘要: A composition comprising oxybutynin, a dosage form comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
摘要翻译: 公开了包含奥昔布宁的组合物,包含奥昔布宁的剂型和用于奥昔布宁治疗的奥昔布宁的施用方法。
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公开(公告)号:US5620700A
公开(公告)日:1997-04-15
申请号:US437471
申请日:1995-05-09
申请人: Randall G. Berggren , David J. Enscore , Susan M. Marks , James L. Osborne , Patrick S.-L. Wong , Wouter E. Roorda
发明人: Randall G. Berggren , David J. Enscore , Susan M. Marks , James L. Osborne , Patrick S.-L. Wong , Wouter E. Roorda
CPC分类号: A61C19/063 , A61K47/34
摘要: The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days.
摘要翻译: 本发明涉及可用于将诸如抗生素的药物递送到患病组织袋(例如牙周袋)中的材料。 该材料优选为生物可腐蚀的低聚物或聚合物。 包含药物的低聚物或聚合物被加热,然后优选通过注射递送到生理上相容的升高的温度下的组织袋中。 一旦将生物可蚀解材料注入到口袋中,则该材料冷却到口袋的体温。 当它冷却时,材料硬化并保持在组织袋中的适当位置。 硬化的材料在口袋中传播并在几天的时间内释放药物。
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公开(公告)号:US5674895A
公开(公告)日:1997-10-07
申请号:US445849
申请日:1995-05-22
IPC分类号: A61K9/24 , A61K9/00 , A61K9/20 , A61K31/215 , A61K31/216 , A61K31/221 , A61K47/38 , A61P13/02 , A61P15/00 , A01N37/44 , A61K31/24
CPC分类号: A61K9/2054 , A61K31/216 , A61K31/221 , A61K9/0004 , A61K9/2031
摘要: A composition comprising oxybutynin and a device comprising oxybutynin are disclosed for oxybutynin therapy.
摘要翻译: 公开了包含奥昔布宁的组合物和包含奥昔布宁的装置,用于奥昔布宁治疗。
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公开(公告)号:US06919092B2
公开(公告)日:2005-07-19
申请号:US09785805
申请日:2001-02-16
IPC分类号: A61K9/00 , A61K9/20 , A61K31/216 , A61K31/221
CPC分类号: A61K9/209 , A61K9/0004 , A61K9/2031 , A61K9/2054 , A61K31/216 , A61K31/221 , A61K31/24
摘要: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.
摘要翻译: 公开了组合物和剂型,其包含单独的奥昔布宁或伴随着另一种用于治疗的药物。 公开了用于单独/或伴随不同药物的奥昔布宁或根据用于单独治疗失禁的治疗程序以及用于其它治疗的奥昔布宁和不同药物施用奥昔布宁的方法。
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公开(公告)号:US5912268A
公开(公告)日:1999-06-15
申请号:US806773
申请日:1997-02-26
IPC分类号: A61K9/00 , A61K9/20 , A61K9/22 , A61K31/216 , A61K31/221 , A01N37/44
CPC分类号: A61K9/0004 , A61K31/216 , A61K31/221 , A61K9/2031 , A61K9/2054
摘要: A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
摘要翻译: 公开了包含奥昔布宁的组合物,包含奥昔布宁的装置和用于奥昔布宁治疗的给予奥昔布宁的方法。
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公开(公告)号:US5840754A
公开(公告)日:1998-11-24
申请号:US706576
申请日:1996-09-05
IPC分类号: A61K9/24 , A61K9/00 , A61K9/20 , A61K31/215 , A61K31/216 , A61K31/221 , A61K47/38 , A61P13/02 , A61P15/00 , A01N37/44
CPC分类号: A61K9/2054 , A61K31/216 , A61K31/221 , A61K9/0004 , A61K9/2031
摘要: A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
摘要翻译: 公开了包含奥昔布宁的组合物,包含奥昔布宁的装置和用于奥昔布宁治疗的给予奥昔布宁的方法。
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公开(公告)号:US5783205A
公开(公告)日:1998-07-21
申请号:US843682
申请日:1997-04-10
申请人: Randall G. Berggren , David J. Enscore , Susan M. Marks , James L. Osborne , Patrick S.-L. Wong , Wouter E. Roorda
发明人: Randall G. Berggren , David J. Enscore , Susan M. Marks , James L. Osborne , Patrick S.-L. Wong , Wouter E. Roorda
CPC分类号: A61C19/063 , A61K6/0067 , A61K9/0063 , A61K47/34
摘要: The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days.
摘要翻译: 本发明涉及可用于将诸如抗生素的药物递送到患病组织袋(例如牙周袋)中的材料。 该材料优选为生物可腐蚀的低聚物或聚合物。 包含药物的低聚物或聚合物被加热,然后优选通过注射递送到生理上相容的升高的温度下的组织袋中。 一旦将生物可蚀解材料注入到口袋中,则该材料冷却到口袋的体温。 当它冷却时,材料硬化并保持在组织袋中的适当位置。 硬化的材料在口袋中传播并在几天的时间内释放药物。
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公开(公告)号:US06262115B1
公开(公告)日:2001-07-17
申请号:US09280309
申请日:1999-03-29
IPC分类号: A01N3744
CPC分类号: A61K9/209 , A61K9/0004 , A61K9/2031 , A61K9/2054 , A61K31/216 , A61K31/221 , A61K31/24
摘要: A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.
摘要翻译: 公开了组合物和剂型,其包含单独的奥昔布宁或伴随着另一种用于治疗的药物。 公开了用于单独/或伴随不同药物的奥昔布宁或根据用于单独治疗失禁的治疗程序以及用于其它治疗的奥昔布宁和不同药物施用奥昔布宁的方法。
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