发明授权
- 专利标题: Yeast strains with stable integration of heterologous genes
- 专利标题(中): 具有稳定整合异源基因的酵母菌株
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申请号: US182127申请日: 1994-01-13
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公开(公告)号: US5635369A公开(公告)日: 1997-06-03
- 发明人: Denis Pompon , Christophe Cullin , Gilles Truan , Philippe Urban , Piotr Slonimski
- 申请人: Denis Pompon , Christophe Cullin , Gilles Truan , Philippe Urban , Piotr Slonimski
- 申请人地址: FRX Paris Cedex
- 专利权人: Centre National De La Recherche Scientifique
- 当前专利权人: Centre National De La Recherche Scientifique
- 当前专利权人地址: FRX Paris Cedex
- 优先权: FRX9108884 19910715
- 主分类号: C07K14/80
- IPC分类号: C07K14/80 ; C12N1/18 ; C12N1/19 ; C12N9/02 ; C12N9/16 ; C12N15/09 ; C12N15/81 ; C12P21/02 ; C12N1/15
摘要:
Yeast strains and a method of expression in yeast of the monooxygenase activity of heterologous cytochromes P450 are disclosed. Within the genome of the yeast strain, genes for NADPH-cytochrome P450 reductase and cytochrome b5 are stably integrated and coexpressed. The genome is transformed with a plasmid carrying a cassette for the expression of a heterologous P450 gene.
公开/授权文献
- US4917968A High temperature corrosion resistant composite structure 公开/授权日:1990-04-17