发明授权
- 专利标题: Marcrocyclic amide and urea immunomodulators
- 专利标题(中): 大环酰胺和尿素免疫调节剂
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申请号: US636746申请日: 1996-04-19
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公开(公告)号: US5643918A公开(公告)日: 1997-07-01
- 发明人: Rolf Wagner , Jay R. Luly , Yat Sun Or
- 申请人: Rolf Wagner , Jay R. Luly , Yat Sun Or
- 申请人地址: IL Abbott Park
- 专利权人: Abbott Laboratories
- 当前专利权人: Abbott Laboratories
- 当前专利权人地址: IL Abbott Park
- 主分类号: C07D487/14
- IPC分类号: C07D487/14 ; C07D491/20 ; C07D498/04 ; C07D498/14 ; C07D498/18 ; C07D498/22 ; C07D513/14 ; C07D513/18 ; C07F7/18 ; C07F9/6561 ; C07H19/01 ; A61K31/435
摘要:
Immunomodulatory macrocyclic compounds having the formula: ##STR1## and pharmaceutically-acceptable salts, esters, amides and prodrugs thereof, as well as pharmaceutical compositions containing the same, which possess immunosuppressive, antimicrobial, antifungal, antiviral, antiinflammatory and antiproliferative activity, as well as the ability to reverse chemotherapeutic drug resistance.
公开/授权文献
- US4036780A Catalyst for the preparation of maleic anhydride 公开/授权日:1977-07-19