发明授权
- 专利标题： Octahydronaphthalene oxime compounds for cholesterol synthesis inhibition
- 专利标题（中）： 八氢萘肟化合物用于胆固醇合成抑制
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申请号： US399500申请日： 1995-03-07
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公开(公告)号： US5658942A公开(公告)日： 1997-08-19
- 发明人: Masaaki Kurabayashi , Hiroshi Kogen , Hiroshi Kadokawa , Hideshi Kurihara , Kazuo Hasegawa , Masao Kuroda
- 申请人： Masaaki Kurabayashi , Hiroshi Kogen , Hiroshi Kadokawa , Hideshi Kurihara , Kazuo Hasegawa , Masao Kuroda
- 申请人地址： JPX Tokyo
- 专利权人： Sankyo Company, Limited
- 当前专利权人： Sankyo Company, Limited
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX62-271512 19871027
- 主分类号： C07C251/44
- IPC分类号： C07C251/44 ; C07C251/50 ; C07D295/088 ; C07D309/30 ; C07D405/12 ; C07D407/12 ; C07D413/12 ; A61K31/35 ; A61K31/20 ; A61K31/42 ; A61K31/435
摘要：
Compounds of formula (I): ##STR1## in which: R represents hydrogen, methyl or hydroxy; X represents an alkyl, alkenyl, cycloalkyl, aryl, aralkyl, or heterocyclic group; A represents a single bond, or an alkylene, alkenylene, alkynylene or alkadienylene group; Y represents hydrogen, or an aryl, cycloalkyl or heterocyclic group; have valuable antihypercholesteremic activities and may be used in the treatment of disorders arising from a blood cholesterol imbalance in humans and other animals.
公开/授权文献
- US4488551A Pacifier with flow regulating means 公开/授权日：1984-12-18
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