发明授权
- 专利标题： Serine protease and serine protease gene
- 专利标题（中）： 丝氨酸蛋白酶和丝氨酸蛋白酶基因
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申请号： US385230申请日： 1995-02-08
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公开(公告)号： US5661000A公开(公告)日： 1997-08-26
- 发明人: Yosuke Aoki , Kiyoshi Okano , Masanobu Naruto , Hirohiko Shimizu , Haruji Nakamura
- 申请人： Yosuke Aoki , Kiyoshi Okano , Masanobu Naruto , Hirohiko Shimizu , Haruji Nakamura
- 申请人地址： JPX
- 专利权人： Toray Industries, Inc.
- 当前专利权人： Toray Industries, Inc.
- 当前专利权人地址： JPX
- 优先权： JPX62-50676 19870305; JPX62-225540 19870909
- 主分类号： C12N9/64
- IPC分类号： C12N9/64 ; C12P21/06 ; C07H21/04 ; C12N9/50 ; C12N15/63
摘要：
The present invention offers the serine protease exhibiting a biological activity which a polypeptide having an amino acid sequence shown in FIG. 1 shows, the serine protease precursor where a cleavable peptide or signal peptide connects with the N-terminal of the said serine protease, and the gene encoding them. The serine protease being useful in medical treatment fields can be manufactured in large quantities by the present invention.Moreover, the present invention offers the DNA sequence coding a transcription controlling region contained in the chromosomal gene of the serine protease of a human myeloid cell. This sequence is the transcription controlling region being necessary for the gene expression being specific to a human leukocyte or erythrocyte.
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