Invention Grant
- Patent Title: Matrix for sustained-release preparation
- Patent Title (中): 用于缓释制剂的基质
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Application No.: US723152Application Date: 1996-09-30
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Publication No.: US5665394APublication Date: 1997-09-09
- Inventor: Yasutaka Igari , Akira Saikawa , Kayoko Okamoto , Shigeru Kamei , Masahisa Oka , Atsunori Sano
- Applicant: Yasutaka Igari , Akira Saikawa , Kayoko Okamoto , Shigeru Kamei , Masahisa Oka , Atsunori Sano
- Applicant Address: JPX Osaka JPX Osaka
- Assignee: Takeda Chemical Industries, Ltd.,Wako Purechemical Industries, Ltd.
- Current Assignee: Takeda Chemical Industries, Ltd.,Wako Purechemical Industries, Ltd.
- Current Assignee Address: JPX Osaka JPX Osaka
- Priority: JPX6-022858 19940221; JPX6-022880 19940221
- Main IPC: A61K9/16
- IPC: A61K9/16 ; C08G63/06 ; A61K9/50 ; A61F2/02 ; A61F9/02 ; A61K9/48
Abstract:
The present invention relates to a matrix for sustained-release preparation comprising an ester formed at a terminal carboxyl group of a straight-chain polyester which essentially consists of an .alpha.-hydroxymonocarboxylic acid. The matrix is stable to light, heat, moisture, coloring etc., and is of low toxicity. The sustained-release preparation produced by using the ester of the present invention offers stable drug release over an extended period of time, ensuring sustained stable effect. Furthermore, the sustained-release preparation does not show excess drug release just after administration.
Public/Granted literature
- US4661877A Transformer protective relay Public/Granted day:1987-04-28
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