发明授权
- 专利标题: Matrix for sustained-release preparation
- 专利标题(中): 用于缓释制剂的基质
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申请号: US723152申请日: 1996-09-30
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公开(公告)号: US5665394A公开(公告)日: 1997-09-09
- 发明人: Yasutaka Igari , Akira Saikawa , Kayoko Okamoto , Shigeru Kamei , Masahisa Oka , Atsunori Sano
- 申请人: Yasutaka Igari , Akira Saikawa , Kayoko Okamoto , Shigeru Kamei , Masahisa Oka , Atsunori Sano
- 申请人地址: JPX Osaka JPX Osaka
- 专利权人: Takeda Chemical Industries, Ltd.,Wako Purechemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.,Wako Purechemical Industries, Ltd.
- 当前专利权人地址: JPX Osaka JPX Osaka
- 优先权: JPX6-022858 19940221; JPX6-022880 19940221
- 主分类号: A61K9/16
- IPC分类号: A61K9/16 ; C08G63/06 ; A61K9/50 ; A61F2/02 ; A61F9/02 ; A61K9/48
摘要:
The present invention relates to a matrix for sustained-release preparation comprising an ester formed at a terminal carboxyl group of a straight-chain polyester which essentially consists of an .alpha.-hydroxymonocarboxylic acid. The matrix is stable to light, heat, moisture, coloring etc., and is of low toxicity. The sustained-release preparation produced by using the ester of the present invention offers stable drug release over an extended period of time, ensuring sustained stable effect. Furthermore, the sustained-release preparation does not show excess drug release just after administration.
公开/授权文献
- US4661877A Transformer protective relay 公开/授权日:1987-04-28
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