发明授权
US5665735A Unbridged bis-aryl carbinol derivatives compositions and methods of use
失效
未桥连的双芳基甲醇衍生物组合物和使用方法
- 专利标题: Unbridged bis-aryl carbinol derivatives compositions and methods of use
- 专利标题(中): 未桥连的双芳基甲醇衍生物组合物和使用方法
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申请号: US459149申请日: 1995-06-02
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公开(公告)号: US5665735A公开(公告)日: 1997-09-09
- 发明人: Richard Friary , John J. Piwinski , Jesse K. Wong
- 申请人: Richard Friary , John J. Piwinski , Jesse K. Wong
- 申请人地址: NJ Kenilworth
- 专利权人: Schering Corporation
- 当前专利权人: Schering Corporation
- 当前专利权人地址: NJ Kenilworth
- 主分类号: A61K31/4427
- IPC分类号: A61K31/4427 ; A61K31/4433 ; A61K31/445 ; A61P11/00 ; A61P37/08 ; C07D401/06 ; C07D401/14 ; C07D409/14 ; C07D417/14 ; C07D211/22 ; C07D211/26 ; C07D211/32
摘要:
Disclosed is a compound of Formula 1.0: ##STR1## or a pharmaceutically acceptable salt or solvate thereof, wherein: AR.sup.1 represents ##STR2## AR.sup.2 represents ##STR3## or a five-membered heterocyclic aromatic group selected from the group consisting of Formulas I to XII, wherein the substitutable carbon atoms of the five-membered heterocyclic group can optionally be substituted with a group R.sup.1.Also disclosed are pharmaceutical compositions containing compounds of Formula 1.0.Further disclosed is a method for treating asthma, allergy and inflammation by administering an anti-asthmatic, anti-allergic or anti-inflammatory, respectively, effective amount of a compound of Formula 1.0.
公开/授权文献
- US4546447A Division apparatus 公开/授权日:1985-10-08
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