发明授权
- 专利标题： Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders
- 专利标题（中）： 可用于治疗抑郁症和强迫症的氨基肟
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申请号： US285668申请日： 1994-08-03
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公开(公告)号： US5665756A公开(公告)日： 1997-09-09
- 发明人: Gregory M. Shutske , Brian S. Freed , John D. Tomer, IV , R. Richard L. Hamer
- 申请人： Gregory M. Shutske , Brian S. Freed , John D. Tomer, IV , R. Richard L. Hamer
- 申请人地址： OH Cincinnati
- 专利权人： Hoechst Marion Roussel, Inc.
- 当前专利权人： Hoechst Marion Roussel, Inc.
- 当前专利权人地址： OH Cincinnati
- 主分类号： C07D233/60
- IPC分类号： C07D233/60 ; A61K31/415 ; A61K31/4184 ; A61K31/4427 ; A61K31/445 ; A61K31/454 ; A61P25/00 ; A61P25/20 ; A61P25/24 ; A61P25/26 ; C07D211/14 ; C07D211/32 ; C07D233/54 ; C07D233/61 ; C07D235/26 ; C07D401/04 ; C07D401/12 ; C07D521/00 ; C07C251/58 ; A61K31/15 ; C07C233/61
摘要：
Novel aminoalkyloximes of the formula ##STR1## wherein: a. X is hydrogen, loweralkyl, loweralkoxy, halogen, trifluoromethyl, or a group of the formula ##STR2## wherein Y is hydrogen or loweralkyl, and p is 1 or 2; b. A is a group of the formula ##STR3## c. R.sup.1 and R.sup.2 are independently hydrogen or lowerakyl; and d. m is 2 to 6 and n is 0, or 2 to 6, inclusive, serotonin reuptake inhibitors, useful for treating depression and obsessive compulsive disorders are described. Also described are precursors of and processes for the preparation of such aminoakyloximes.
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