发明授权
- 专利标题： Aziridine derivatives, their production and use
- 专利标题（中）： 氮丙啶衍生物，其生产和使用
-
申请号： US513896申请日： 1995-09-05
-
公开(公告)号： US5668128A公开(公告)日： 1997-09-16
- 发明人: Shigetoshi Tsubotani , Masayuki Takizawa , Mikio Shirasaki , Junji Mizoguchi , Yoshiaki Shimizu
- 申请人： Shigetoshi Tsubotani , Masayuki Takizawa , Mikio Shirasaki , Junji Mizoguchi , Yoshiaki Shimizu
- 申请人地址： JPX Osaka
- 专利权人： Takeda Chemical Industries, Ltd.
- 当前专利权人： Takeda Chemical Industries, Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： JPX6-074621 19940413; JPX6-269175 19941101
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07D203/08 ; C07D203/18 ; C07D401/12 ; C07D405/12 ; C07D409/12 ; C07D417/12 ; C07K5/02 ; C07K5/078 ; C07D203/16 ; A61K31/33 ; A61K31/535 ; C07D413/00
摘要：
The present invention relates to a compound of the formula: ##STR1## wherein R.sub.1 and Q are independently an optionally esterified or amidated carboxyl group; R.sub.2 is hydrogen, an acyl group or an optionally substituted hydrocarbon residue; X is a divalent hydrocarbon residue which may be substituted; or a salt thereof, which is useful as prophylactic and therapeutic agents of bone diseases and as agents for inhibiting thiol protease.