发明授权
US5674909A Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene active on the
cardiovascular system
失效
2-氨基-1,2,3,4-四氢萘在心血管系统上有活性的衍生物
- 专利标题: Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene active on the cardiovascular system
- 专利标题(中): 2-氨基-1,2,3,4-四氢萘在心血管系统上有活性的衍生物
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申请号: US465636申请日: 1995-06-06
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公开(公告)号: US5674909A公开(公告)日: 1997-10-07
- 发明人: Stefania Montanari , Paolo Cavalleri , Cristina Fraire , Gian Carlo Grancini , Mauro Napoletano , Francesco Santangelo
- 申请人: Stefania Montanari , Paolo Cavalleri , Cristina Fraire , Gian Carlo Grancini , Mauro Napoletano , Francesco Santangelo
- 申请人地址: ITX Bresso
- 专利权人: Zambon Group
- 当前专利权人: Zambon Group
- 当前专利权人地址: ITX Bresso
- 优先权: ITXMI94A1868 19940913
- 主分类号: C07D295/12
- IPC分类号: C07D295/12 ; A61K31/10 ; A61K31/135 ; A61K31/165 ; A61K31/18 ; A61K31/24 ; A61K31/335 ; A61K31/40 ; A61K31/403 ; A61K31/404 ; A61K31/415 ; A61K31/4184 ; A61K31/42 ; A61K31/423 ; A61K31/425 ; A61K31/428 ; A61K31/47 ; A61K31/472 ; A61K31/495 ; A61K31/496 ; A61P9/00 ; A61P9/12 ; A61P13/02 ; A61P15/00 ; C07C59/90 ; C07C211/42 ; C07C215/64 ; C07C215/68 ; C07C215/80 ; C07C217/20 ; C07C217/60 ; C07C217/74 ; C07C229/08 ; C07C229/38 ; C07C233/43 ; C07C235/20 ; C07C235/34 ; C07C237/22 ; C07C237/30 ; C07C271/30 ; C07C309/00 ; C07C309/45 ; C07C309/46 ; C07C311/05 ; C07C311/08 ; C07C311/37 ; C07C317/22 ; C07C317/32 ; C07C317/44 ; C07C323/00 ; C07C323/24 ; C07C323/25 ; C07D209/08 ; C07D217/04 ; C07D217/14 ; C07D235/26 ; C07D263/58 ; C07D277/64 ; C07D277/68 ; C07D277/82 ; C07D295/04 ; C07D295/13 ; C07D317/58 ; C07D319/16 ; C07D319/20
摘要:
Compounds of formula ##STR1## wherein R, R', R", R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, X, Y, m, n and p have the meanings reported in the description; and their pharmaceutically acceptable salts are described. The compounds of formula I are useful in the treatment of arterial hypertension and congestive heart failure, of renal failure, of peripheral arteriopathies, of cerebrovascular insufficiencies and of ischemic cardiopathy.
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