发明授权
US5681721A Bifunctional urokinase variants with improved fibrinolytic
characteristics and thrombin inhibiting effect
失效
双功能尿激酶变体具有改善的纤维蛋白溶解特征和凝血酶抑制作用
- 专利标题: Bifunctional urokinase variants with improved fibrinolytic characteristics and thrombin inhibiting effect
- 专利标题(中): 双功能尿激酶变体具有改善的纤维蛋白溶解特征和凝血酶抑制作用
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申请号: US093741申请日: 1993-07-20
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公开(公告)号: US5681721A公开(公告)日: 1997-10-28
- 发明人: Gerd J. Steffens , Stephan Wnendt , Johannes Schneider , Regina Heinzel-Wieland , Derek John Saunders
- 申请人: Gerd J. Steffens , Stephan Wnendt , Johannes Schneider , Regina Heinzel-Wieland , Derek John Saunders
- 申请人地址: DEX Aachen
- 专利权人: Gruenenthal GmbH
- 当前专利权人: Gruenenthal GmbH
- 当前专利权人地址: DEX Aachen
- 优先权: DEX4323754.1 19930715
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K38/00 ; A61K38/46 ; A61K38/49 ; A61K38/55 ; A61P7/02 ; C07K14/81 ; C07K19/00 ; C12N9/72 ; C12N15/58 ; C12N15/62 ; C12R1/19 ; A61K38/36
摘要:
Bifunctional urokinase variants possessing improved fibrinolytic properties and thrombin inhibitory activities, plasmids used in the production of these polypeptides, as well as thrombolytic agents containing one of the bifunctional urokinase variants as active ingredient are described.
公开/授权文献
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