发明授权
US5684206A .beta.-aminovinyl ketones, a preparation process and their use in the
preparation of .beta.-diketones
失效
β-氨基乙烯基酮,其制备方法及其在制备β-二酮中的应用
- 专利标题: .beta.-aminovinyl ketones, a preparation process and their use in the preparation of .beta.-diketones
- 专利标题(中): β-氨基乙烯基酮,其制备方法及其在制备β-二酮中的应用
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申请号: US569266申请日: 1996-03-20
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公开(公告)号: US5684206A公开(公告)日: 1997-11-04
- 发明人: Michel Casado , Pierre Le Roy , Virginie Pevere
- 申请人: Michel Casado , Pierre Le Roy , Virginie Pevere
- 申请人地址: FRX Lyons Cedex
- 专利权人: Rhone-Poulenc Argochimie
- 当前专利权人: Rhone-Poulenc Argochimie
- 当前专利权人地址: FRX Lyons Cedex
- 优先权: FRX9307867 19930623
- 主分类号: B01J27/02
- IPC分类号: B01J27/02 ; B01J27/10 ; C07B61/00 ; C07C45/42 ; C07C49/217 ; C07C49/563 ; C07C69/78 ; C07C225/16 ; C07C319/20 ; C07C323/32 ; C07C49/76
摘要:
Novel .beta.-aminovinyl ketones of the general formula ##STR1## wherein R.sup.1 is, in particular, an alkenyl, alkynyl, cycloalkyl or cycloalkenyl group; R.sup.2 is, in particular, an electron-attracting substituent such as nitro, acyl, ester, alkylthio, carbamoyl, thiocarbamoyl or haloalkyl; R.sup.3 is, in particular, an alkyl or alkoxy group or a halogen atom; n is 1 or 2 and m is 0, 1, 2 or 3. A method for preparing such compounds by carrying out a condensation reaction between ketone R.sup.1 --CO--CH.sub.3 and, in particular, benzonitrile substituted by (R.sup.2).sub.n and optionally (R.sup.3).sub.m, in the presence of a strong base, as well as a process employing said .beta.-aminovinyl ketones of general formula (VI) for preparing the corresponding .beta.-diketones, are also disclosed.