发明授权
US5686068A Isolated peptides derived from MAGE-2, cytolytic T cells specific to
complexes of peptide and HLA-A2 molecules, and uses thereof
失效
衍生自MAGE-2的分离的肽,对肽和HLA-A2分子的复合物特异的细胞溶解性T细胞及其用途
- 专利标题: Isolated peptides derived from MAGE-2, cytolytic T cells specific to complexes of peptide and HLA-A2 molecules, and uses thereof
- 专利标题(中): 衍生自MAGE-2的分离的肽,对肽和HLA-A2分子的复合物特异的细胞溶解性T细胞及其用途
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申请号: US687226申请日: 1996-07-25
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公开(公告)号: US5686068A公开(公告)日: 1997-11-11
- 发明人: Cornelius J. M. Melief , M. W. Visseren , Sjoerd van der Burg , Pierre van der Bruggen , Thierry Boon-Falleur
- 申请人: Cornelius J. M. Melief , M. W. Visseren , Sjoerd van der Burg , Pierre van der Bruggen , Thierry Boon-Falleur
- 申请人地址: NY New York NLX Leiden
- 专利权人: Ludwig Institute for Cancer Research,Leiden University
- 当前专利权人: Ludwig Institute for Cancer Research,Leiden University
- 当前专利权人地址: NY New York NLX Leiden
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61K35/26 ; A61K38/00 ; A61K38/04 ; A61K39/395 ; A61P35/00 ; A61P37/00 ; C07K5/00 ; C07K7/06 ; C07K7/08 ; C07K14/47 ; C07K14/705 ; C07K14/74 ; C07K16/28 ; C12N5/00 ; C12P21/08 ; A61K38/08 ; C07K14/82 ; C12N5/06
摘要:
New peptides derived from the MAGE-2 molecule and which bind to HLA-A*0201 molecules are disclosed. Some of these are especially useful because, when complexed to their HLA-A*0201 partner molecules, they induce CTL proliferation.
公开/授权文献
- USD285363S Pharmaceutical tablet 公开/授权日:1986-08-26
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