发明授权
US5695994A Isolated cytolytic T cells specific for complexes of MAGE related
peptides and HLA molecules
失效
对MAGE相关肽和HLA分子的复合物分离的分离的溶细胞T细胞
- 专利标题: Isolated cytolytic T cells specific for complexes of MAGE related peptides and HLA molecules
- 专利标题(中): 对MAGE相关肽和HLA分子的复合物分离的分离的溶细胞T细胞
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申请号: US443341申请日: 1995-05-17
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公开(公告)号: US5695994A公开(公告)日: 1997-12-09
- 发明人: Thierry Boon-Falleur , Pierre van der Bruggen , Etienne De Plaen , Christophe Lurguin , Catia Traversari , Beatrice Gaugler , Benoit Van den Eynde
- 申请人: Thierry Boon-Falleur , Pierre van der Bruggen , Etienne De Plaen , Christophe Lurguin , Catia Traversari , Beatrice Gaugler , Benoit Van den Eynde
- 申请人地址: NY New York
- 专利权人: Ludwig Institute for Cancer Research
- 当前专利权人: Ludwig Institute for Cancer Research
- 当前专利权人地址: NY New York
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; A61K35/16 ; A61K38/00 ; A61K39/00 ; A61K39/395 ; A61P37/00 ; C07K1/00 ; C07K7/06 ; C07K14/00 ; C07K14/47 ; C07K14/705 ; C07K16/28 ; C07K16/30 ; C07K17/00 ; C12N5/10 ; C12N15/09 ; C12N15/11 ; C12P21/02 ; C12P21/08 ; G01N33/574 ; G01N33/577 ; C12N5/06 ; C12N5/08
摘要:
The invention involves a nonapeptide derived from the tumor rejection antigen precursor encoded by gene MAGE-3. This nonapeptide is presented by HLA molecules HLA-A1. The resulting complexes are identified by cytolytic T cells. Such recognition may be used in diagnostics, or therapeutically.
公开/授权文献
- USD325403S Maze game 公开/授权日:1992-04-14
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