发明授权
US5700848A Gel compositions prepared from crosslinkable polysaccharides,
polycations and/or lipids and uses therefor
失效
由交联性多糖,聚阳离子和/或脂质制备的凝胶组合物及其用途
- 专利标题: Gel compositions prepared from crosslinkable polysaccharides, polycations and/or lipids and uses therefor
- 专利标题(中): 由交联性多糖,聚阳离子和/或脂质制备的凝胶组合物及其用途
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申请号: US472191申请日: 1995-06-07
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公开(公告)号: US5700848A公开(公告)日: 1997-12-23
- 发明人: Patrick Soon-Shiong , Neil P. Desai , Paul A. Sandford , Roswitha A. Heintz , Soebianto Sojomihardjo
- 申请人: Patrick Soon-Shiong , Neil P. Desai , Paul A. Sandford , Roswitha A. Heintz , Soebianto Sojomihardjo
- 申请人地址: CA Santa Monica
- 专利权人: Vivorx Inc.
- 当前专利权人: Vivorx Inc.
- 当前专利权人地址: CA Santa Monica
- 主分类号: A61K9/50
- IPC分类号: A61K9/50 ; A61F13/00 ; A61F13/02 ; A61K9/127 ; A61K9/16 ; A61K47/30 ; A61L15/00 ; A61L15/58 ; A61L24/04 ; A61L24/08 ; A61L26/00 ; A61L27/38 ; C08B37/00 ; C08B37/08 ; C08F2/50 ; C08F290/00 ; C08F290/08 ; C08F290/10 ; C12N11/04
摘要:
The present invention relates to a new form of biocompatible materials (e.g., lipids, polycations, polysaccharides) which are capable of undergoing free radical polymerization, e.g., by using certain sources of light; methods of modifying certain synthetic and naturally occurring biocompatible materials to make polymerizable microcapsules containing biological material coated with said polymerizable materials, composites of said polymerizable materials, methods of making microcapsules and encapsulating biological materials therein, and apparatus for making microcapsules containing biological cells (particularly islets of Langerhans) coated with polymerizable alginate or with a composite thereof (e.g., alginate and PEG). The present invention also relates to drug delivery systems relating to the foregoing, as well as bioadhesives and wound dressings made utilizing the foregoing technology.
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