An amplifier circuit with improved turn-on transient operation includes a differential amplifier and a selectively variable reference generator for controlling the amplifier output during circuit turn-on. The amplifier is biased by a single power supply and its differential inputs are driven by a reference voltage from the reference generator and a single-ended input signal. Following circuit turn-on, the selectively variable reference voltage, generated by charging the bypass capacitor with a constant current source, charges in a linear manner from ground potential toward its final value of, typically, half of the power supply voltage. This allows improved turn-on transient operation to be realized, e.g. reduced "pops" and "clicks" upon circuit turn-on, while giving the user increased flexibility in selecting the sizes of the reference voltage bypass capacitor and the input signal coupling capacitor.