Column packings for liquid chromatography comprising porous granules which have hydrophilic surfaces prepared by calcining a crystalline clay mineral having a fibrous structure. Median pore diameter of the porous ceramic granules is in the range of from 0.001 .mu.m to 0.01 .mu.m. The crystalline clay mineral can be sepiolite or attapulgite. The column packings for liquid chromatography have high mechanical strength, are presssure resistant and very stable to elutants having a high pH value and/or a high polarity so that the separating characteristics thereof are not changed even after long use.