发明授权
- 专利标题： Transgenic rats containing at least one human gene which participates in blood pressure control
- 专利标题（中）： 含有至少一种参与血压控制的人基因的转基因大鼠
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申请号： US373495申请日： 1995-01-17
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公开(公告)号： US5731489A公开(公告)日： 1998-03-24
- 发明人: Detlev Ganten , John Mullins , Kazuo Murakami
- 申请人： Detlev Ganten , John Mullins , Kazuo Murakami
- 申请人地址： DEX Heidelberg
- 专利权人： Ganten; Detlev
- 当前专利权人： Ganten; Detlev
- 当前专利权人地址： DEX Heidelberg
- 优先权： DEX4126968.3 19910814
- 主分类号： A01K67/027
- IPC分类号： A01K67/027 ; C07K7/14 ; C12N9/64 ; C12N15/09 ; C12N15/15 ; C12N15/57 ; C12N15/85 ; C12N15/00 ; A61K38/46
摘要：
The present invention relates to transgenic rats in the genome of which at least one human gene is integrated the gene product of which participates in blood pressure control. More specifically, the invention relates to transgenic rats and their offspring exhibiting increased blood pressure (>90/>140 mm Hg) or high blood pressure (>95/>160 mm Hg). Finally, the invention relates to processes for the production of the transgenic rats of the present invention and their offspring and their use for pharmacological tests.
公开/授权文献
- US5014768A Chill plate having high heat conductivity and wear resistance 公开/授权日：1991-05-14
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