- 专利标题： N-substituted glutamic acid derivatives with interleukin-1 .beta. converting enzyme inhibitory activity
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申请号： US700716申请日： 1996-08-13
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公开(公告)号： US5744451A公开(公告)日： 1998-04-28
- 发明人: Hamish John Allen , Subhashis Banerjee , Kenneth Dale Brady , John Cooke Hodges , Catherine Rose Kostlan , Robert Vincent Talanian
- 申请人： Hamish John Allen , Subhashis Banerjee , Kenneth Dale Brady , John Cooke Hodges , Catherine Rose Kostlan , Robert Vincent Talanian
- 申请人地址： NJ Morris Plains DEX Ludwigshafen
- 专利权人： Warner-Lambert Company,BASF A.G.
- 当前专利权人： Warner-Lambert Company,BASF A.G.
- 当前专利权人地址： NJ Morris Plains DEX Ludwigshafen
- 主分类号： C07H5/04
- IPC分类号： C07H5/04 ; A61K31/00 ; A61K31/04 ; A61K31/155 ; A61K31/435 ; A61K31/44 ; A61K31/4409 ; A61K31/4412 ; A61K31/4415 ; A61K31/506 ; A61K31/51 ; A61K31/675 ; A61K38/05 ; A61K38/06 ; A61K38/07 ; A61P3/00 ; A61P3/10 ; A61P9/10 ; A61P13/00 ; A61P13/12 ; A61P27/06 ; A61P43/00 ; C07D213/66 ; C07D417/06 ; C07K1/02 ; C07K5/06 ; C07K5/087 ; C07K14/00 ; G01N33/68 ; A61K38/09
摘要：
The present invention relates to N-substituted derivatives of glutamic acid of pharmaceutical interest, to pharmaceutical compositions which include compounds of the invention and pharmaceutically acceptable carriers, to methods of their preparation, and to their use in purification of interleukin-1.beta. converting enzyme (ICE).
公开/授权文献
- USD291221S Doll 公开/授权日：1987-08-04
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