发明授权
- 专利标题： Filariid nematode cysteine protease proteins
- 专利标题（中）： 丝状线虫半胱氨酸蛋白酶蛋白
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申请号： US463989申请日： 1995-06-05
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公开(公告)号： US5750391A公开(公告)日： 1998-05-12
- 发明人: Cynthia Ann Tripp , Glenn R. Frank , Robert B. Grieve
- 申请人： Cynthia Ann Tripp , Glenn R. Frank , Robert B. Grieve
- 申请人地址： CO Ft. Collins
- 专利权人： Heska Corporation
- 当前专利权人： Heska Corporation
- 当前专利权人地址： CO Ft. Collins
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K38/46 ; A61K38/55 ; A61K39/00 ; A61K39/002 ; A61K39/395 ; A61K48/00 ; A61P5/12 ; A61P33/00 ; A61P33/02 ; A61P33/10 ; A61P43/00 ; C07H21/04 ; C07K14/44 ; C12N1/21 ; C12N5/10 ; C12N9/50 ; C12N9/64 ; C12P21/02 ; C12P21/08 ; C12R1/19 ; C12R1/91 ; C12N9/48
摘要：
The present invention relates to parasite astacin metalloendopeptidase and filariid cysteine protease proteins, nucleic acid molecules having sequences that encode such proteins, antibodies raised against such proteins and compounds that can inhibit the activities of parasite astacin metalloendopeptidases or cysteine proteases. The present invention also includes methods to obtain such nucleic acid molecules, proteins, antibodies and inhibitors. The present invention also includes therapeutic compositions comprising such nucleic acid molecules, proteins, antibodies and inhibitors as well as their use to protect animals from disease caused by parasites, such as heartworm.
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