发明授权
US5770386A Methods and compositions for increasing the sensitivity of a cell to a
DNA damaging agent
失效
提高细胞对DNA损伤剂敏感性的方法和组合物
- 专利标题： Methods and compositions for increasing the sensitivity of a cell to a DNA damaging agent
- 专利标题（中）： 提高细胞对DNA损伤剂敏感性的方法和组合物
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申请号： US886368申请日： 1992-05-20
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公开(公告)号： US5770386A公开(公告)日： 1998-06-23
- 发明人: Patricia S. Steeg , Lance A. Liotta , Ursula Flatow
- 申请人： Patricia S. Steeg , Lance A. Liotta , Ursula Flatow
- 申请人地址： DC Washington
- 专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人地址： DC Washington
- 主分类号： G01N33/577
- IPC分类号： G01N33/577 ; A61K31/70 ; A61K48/00 ; A61P35/00 ; A61P43/00 ; C12N5/10 ; C12N9/12 ; C12N15/09 ; C12P21/02 ; C12Q1/02 ; G01N33/574 ; C12Q1/00 ; G01N33/573
摘要：
The invention provides a method of increasing the sensitivity of a cell to a DNA damaging agent comprising increasing the amount of an NM23 in the cell. The method is especially useful for increasing the sensitivity of tumor cells to chemotherapy and radiation.
公开/授权文献
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