发明授权
- 专利标题： Heterocyclically substituted phenylacetic acid derivatives and their use in medicaments
- 专利标题（中）： 杂环取代的苯乙酸衍生物及其在药物中的应用
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申请号： US609366申请日： 1996-03-01
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公开(公告)号： US5776964A公开(公告)日： 1998-07-07
- 发明人: Ulrich Muller , Klaus Mohrs , Jurgen Dressel , Rudolf Hanko , Walter Hubsch , Michael Matzke , Ulrich Niewohner , Siegfried Raddatz , Thomas Kramer , Matthias Muller-Gliemann , Hans-Peter Bellemann , Martin Beuck , Stanislav Kazda , Stefan Wohlfeil
- 申请人： Ulrich Muller , Klaus Mohrs , Jurgen Dressel , Rudolf Hanko , Walter Hubsch , Michael Matzke , Ulrich Niewohner , Siegfried Raddatz , Thomas Kramer , Matthias Muller-Gliemann , Hans-Peter Bellemann , Martin Beuck , Stanislav Kazda , Stefan Wohlfeil
- 申请人地址： DEX Leverkusen
- 专利权人： Bayer Aktiengesellschaft
- 当前专利权人： Bayer Aktiengesellschaft
- 当前专利权人地址： DEX Leverkusen
- 优先权： DEX4113693.4 19910426; DEX4200954.5 19920116
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; A61K31/41 ; A61K31/415 ; A61K31/4184 ; A61P7/10 ; A61P9/00 ; A61P9/08 ; A61P9/10 ; A61P9/12 ; A61P11/08 ; A61P13/02 ; A61P13/12 ; A61P15/00 ; A61P43/00 ; C07D207/30 ; C07D231/12 ; C07D231/14 ; C07D231/56 ; C07D233/54 ; C07D233/60 ; C07D233/64 ; C07D233/68 ; C07D233/90 ; C07D235/06 ; C07D235/08 ; C07D235/14 ; C07D235/16 ; C07D249/04 ; C07D249/08 ; C07D249/12 ; C07D249/14 ; C07D249/18 ; C07D403/10 ; C07D405/06 ; C07D409/06 ; C07D471/04 ; C07D521/00 ; C07D235/10 ; C07D235/12
摘要：
The invention relates to phenylacetic acid derivatives which are substituted by a five-membered nitrogen heterocycle bonded via an N atom. They are prepared by reaction of phenylacetic acid derivatives substituted with leaving groups with the appropriate nitrogen heterocycles and can be used as active substances in medicaments for the treatment of high blood pressure and atherosclerosis.
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