发明授权
- 专利标题： Device for time lag focusing time-of-flight mass spectrometry
- 专利标题（中）： 时差聚焦飞行时间质谱仪的设备
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申请号： US643708申请日： 1996-05-06
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公开(公告)号： US5777325A公开(公告)日： 1998-07-07
- 发明人: Scot R. Weinberger , Edward P. Donlon , Yevgeny Kaplun , Tor C. Anderson , Liang Li , Larry Russon , Randy Whittal
- 申请人： Scot R. Weinberger , Edward P. Donlon , Yevgeny Kaplun , Tor C. Anderson , Liang Li , Larry Russon , Randy Whittal
- 申请人地址： CA Palo Alto
- 专利权人： Hewlett-Packard Company
- 当前专利权人： Hewlett-Packard Company
- 当前专利权人地址： CA Palo Alto
- 主分类号： H01J49/02
- IPC分类号： H01J49/02 ; H01J49/40
摘要：
A laser desorption ionization instrument for and method of measuring the molecular weight of large organic molecules includes a time of flight mass spectrometer (TOF MS). The TOF MS instrument provides optimized optic design for both DC and TLF modes. The invention further provides dynamic resolution enhancement for a given ejection pulse, along with optimized ion ejection pulses relative to the ion optic elements. The invention also provides means for compensating for difference in total kinetic energy among ions of different mass; high resolution detection means for improved sensitivity for large molecular weight species. The invention further provides x-y-z stage for sample presentation of both standard MALDI and gel or membrane based samples.
公开/授权文献
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