In the case of the electrochemical enzyme biosensor comprising noble metal electrodes, an electrochemical oxidation of pyridine nucleotides takes place, in particular of NADH. The noble metal electrodes have a microtexture rich in surface pores and having catalytic properties, as a result of which the overpotential required for electrochemical oxidation of the pyridine nucleotides is reduced. Owing to these microtextures, the surface area of an electrode is from 3 to 10 times larger than its geometric surface area.