发明授权
US5789193A Increased production of secreted proteins by recombinant eukaryotic cells
失效
通过重组真核细胞增加分泌蛋白质的产生
- 专利标题： Increased production of secreted proteins by recombinant eukaryotic cells
- 专利标题（中）： 通过重组真核细胞增加分泌蛋白质的产生
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申请号： US411706申请日： 1996-01-16
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公开(公告)号： US5789193A公开(公告)日： 1998-08-04
- 发明人: Sirkka Keranen , Markku Aalto , Mika Outola , Hans Ronne , Merja Penttila
- 申请人： Sirkka Keranen , Markku Aalto , Mika Outola , Hans Ronne , Merja Penttila
- 申请人地址： FIX Espoo
- 专利权人： Valtion Teknillinen Tutkimuskeskus
- 当前专利权人： Valtion Teknillinen Tutkimuskeskus
- 当前专利权人地址： FIX Espoo
- 优先权： FIX924494 19921006
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; C12N20060101 ; C12N1/15 ; C12N1/19 ; C12N9/26 ; C12N9/28 ; C12N15/67 ; C12N15/80 ; C12N15/81 ; C12P21/00 ; C12P21/02 ; C12R1/66 ; C12R1/78 ; C12R1/84 ; C12R1/865 ; C12R1/885 ; C12P21/06
摘要：
The invention relates to recombinant DNA technology. Specifically this invention relates to new recombinant eukaryotic cells transformed with SSO genes. Eukaryotic cells transformed with several copies of SSO genes, or overexpressing the Sso protein by some other means, have an increased capacity to produce secreted foreign or endogenous proteins. Further, the said new recombinant cells, when transformed with genes expressing suitable hydrolytic enzymes can utilize appropriate macromolecular compounds more efficiently, which results in increased cell mass production and/or more versatile utilization of the compounds in relevant biotechnical applications.
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