- 专利标题： Covalently linked oligonucleotide minor grove binder conjugates
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申请号： US415370申请日： 1995-04-03
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公开(公告)号： US5801155A公开(公告)日： 1998-09-01
- 发明人: Igor V. Kutyavin , Eugeny A. Lukhtanov , Howard B. Gamper , Rich B. Meyer, Jr.
- 申请人： Igor V. Kutyavin , Eugeny A. Lukhtanov , Howard B. Gamper , Rich B. Meyer, Jr.
- 申请人地址： WA Bothell
- 专利权人： Epoch Pharmaceuticals, Inc.
- 当前专利权人： Epoch Pharmaceuticals, Inc.
- 当前专利权人地址： WA Bothell
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A01N43/04 ; C07D233/02 ; C07D417/00 ; C07H19/00 ; C07H19/23 ; C07H21/00 ; C07H21/02 ; C07H21/04 ; C12Q1/68 ; A01N43/38
摘要：
Minor groove binding molecules are covalently bound to oligonucleotides which in their base sequence are complementary to a target sequence of single stranded or double stranded DNA, RNA or hybrids thereof. The covalently bound oligonucleotide minor groove binder conjugates strongly bind to the target sequence of the complementary strand.
公开/授权文献
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