A negative feedback preamplifier having variable conversion gain control and variable open loop gain control capabilities which can work correctly regardless of semiconductor process variations. The negative feedback preamplifier used to convert an input signal current to a signal in the form of voltage includes: a resistor which determines the current-voltage conversion gain when a small signal current is input to the negative feedback preamplifier; a diode which switches the current-voltage conversion gain when a large signal current is input to the negative feedback preamplifier; a resistor which determines the current-voltage conversion gain when the large signal current is input; a grounded source amplifier including a main FET which is biased such that its transconductance decreases when the large signal current is input; and a bias setting portion (diode) which determines the bias condition associated with the main FET.