发明授权
- 专利标题： Commercial production of aprotinin in plants
- 专利标题（中）： 植物中抑肽酶的商业化生产
-
申请号： US554161申请日： 1995-11-06
-
公开(公告)号： US5824870A公开(公告)日： 1998-10-20
- 发明人: Chris Baszczynski , Thomas Czapla , Elizabeth Hood , Terry EuClaire Meyer , David Peterson , A. Gururaj Rao , James C. Register, III , Derrick Witcher , John A. Howard
- 申请人： Chris Baszczynski , Thomas Czapla , Elizabeth Hood , Terry EuClaire Meyer , David Peterson , A. Gururaj Rao , James C. Register, III , Derrick Witcher , John A. Howard
- 专利权人： Baszczynski; Chris,Czapla; Thomas,Hood; Elizabeth,Meyer; Terry Euclaire,Peterson; David,Rao; A. Gururaj,Register, Iii; James C.,Witcher; Derrick,Howard; John A.
- 当前专利权人： Baszczynski; Chris,Czapla; Thomas,Hood; Elizabeth,Meyer; Terry Euclaire,Peterson; David,Rao; A. Gururaj,Register, Iii; James C.,Witcher; Derrick,Howard; John A.
- 主分类号： C07K14/81
- IPC分类号： C07K14/81 ; C12N15/15 ; C12N15/29 ; C12N15/82 ; C12N15/12 ; A01H5/00
摘要：
A method for commercial production of aprotinin entails heterologous expression of the protein in plants, preferably at a level such that aprotinin accounts for at least 0.1% of the total extracted protein. An aprotinin-expressing plant also has potential of increased insecticidal resistance by virtue of producing the protein. A genetic map of the integration locus allows identification of plants derived from the transgenic plant. This approach also reveals genetic loci on a plant chromosome that support high levels of gene expression and can be used as site of integration for expression of other genes of interest.
公开/授权文献
信息查询
