- 专利标题: Hepatitis C virus epitopes
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申请号: US407410申请日: 1995-03-17
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公开(公告)号: US5843636A公开(公告)日: 1998-12-01
- 发明人: Gregory R. Reyes , Jungsuh P. Kim , Randolph Moeckli , Christian C. Simonsen
- 申请人: Gregory R. Reyes , Jungsuh P. Kim , Randolph Moeckli , Christian C. Simonsen
- 申请人地址: CA Redwood City
- 专利权人: Genelabs Technologies, Inc.
- 当前专利权人: Genelabs Technologies, Inc.
- 当前专利权人地址: CA Redwood City
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61K38/00 ; A61K39/29 ; C07K14/00 ; C07K14/02 ; C07K14/10 ; C07K14/18 ; C12N1/21 ; C12N15/09 ; C12N15/51 ; C12P21/02 ; C12Q1/70 ; C12R1/19 ; G01N33/15 ; G01N33/50 ; G01N33/53 ; G01N33/576 ; C07H17/00 ; C12P21/06
摘要:
Peptide antigens which are immunoreactive with sera from individuals infected with hepatitis C virus (HCV) are disclosed. Several of the antigens are immunologically reactive with antibodies present in individuals identified as having chronic and acute HCV infection. The antigens are useful in diagnostic methods for detecting HCV infection in humans. Also disclosed are corresponding genomic-fragment clones containing polynucleotides encoding the open reading frame sequences for the antigenic peptides.