发明授权
- 专利标题： Modified hemoglobin-like compounds
- 专利标题（中）： 改性血红蛋白样化合物
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申请号： US487431申请日： 1995-06-07
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公开(公告)号： US5844090A公开(公告)日： 1998-12-01
- 发明人: David C. Anderson , Antony J. Mathews , Stephen P. Trimble , Spencer Anthony-Cahill
- 申请人： David C. Anderson , Antony J. Mathews , Stephen P. Trimble , Spencer Anthony-Cahill
- 申请人地址： CO Boulder
- 专利权人： Somatogen, Inc.
- 当前专利权人： Somatogen, Inc.
- 当前专利权人地址： CO Boulder
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K38/00 ; A61K38/16 ; A61K38/42 ; A61P7/08 ; C07K1/18 ; C07K14/805 ; C12N15/12 ; A61K35/14 ; C12P21/02
摘要：
The present invention relates to modified hemoglobin-like compounds. The novel compounds include a globin-like polypeptide containing at least two di-alpha domains and multimeric hemoglobin-like proteins having a core hemoglobin-like moiety directly attached to at least two other hemoglobin-like moieties. The invention also relates to nucleic acid molecules encoding the novel polypeptides. Methods of making the multimeric hemoglobin-like proteins are also provided, as well as compositions containing the proteins.