发明授权
US5852173A TNF receptor death ligand proteins and inhibitors of ligand binding
失效
TNF受体死亡配体蛋白和配体结合抑制剂
- 专利标题： TNF receptor death ligand proteins and inhibitors of ligand binding
- 专利标题（中）： TNF受体死亡配体蛋白和配体结合抑制剂
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申请号： US533901申请日： 1995-09-26
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公开(公告)号： US5852173A公开(公告)日： 1998-12-22
- 发明人: Lih-Ling Lin , Jennifer Chen , Andrea R. Schievella , James Graham
- 申请人： Lih-Ling Lin , Jennifer Chen , Andrea R. Schievella , James Graham
- 申请人地址： MA Cambridge
- 专利权人： Genetics Institute, Inc.
- 当前专利权人： Genetics Institute, Inc.
- 当前专利权人地址： MA Cambridge
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K38/00 ; A61K45/00 ; A61K48/00 ; A61P29/00 ; C07K14/47 ; C07K14/715 ; C07K16/24 ; C12N1/19 ; C12N5/10 ; C12N15/12 ; C12P21/02 ; C07K14/52 ; C12N15/10
摘要：
Novel TNF receptor death domain ("TNF-R1-DD") ligand proteins are disclosed. Polynucleotides encoding the TNF-R1-DD ligand protein are also disclosed, along with vectors, host cells, and methods of making the TNF-R1-DD ligand protein. Pharmaceutical compositions containing the TNF-R1-DD ligand protein, methods of treating inflammatory conditions, and methods of inhibiting TNF-R death domain binding are also disclosed. Methods of identifying inhibitors of TNF-R death domain binding and inhibitors identified by such methods are also disclosed.
公开/授权文献
- USD330725S Writing instrument 公开/授权日：1992-11-03
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