发明授权
- 专利标题: Cloning of a novel G-Protein coupled 7TM receptor
- 专利标题(中): 克隆一种新的G蛋白偶联的7TM受体
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申请号: US788539申请日: 1997-01-24
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公开(公告)号: US5871967A公开(公告)日: 1999-02-16
- 发明人: Usman Shabon , Derk J. Bergsma , Ganesh M. Sathe
- 申请人: Usman Shabon , Derk J. Bergsma , Ganesh M. Sathe
- 申请人地址: PA Philadelphia
- 专利权人: SmithKline Beecham Corporation
- 当前专利权人: SmithKline Beecham Corporation
- 当前专利权人地址: PA Philadelphia
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K38/00 ; A61K39/395 ; A61K45/00 ; A61K48/00 ; C07K14/705 ; C12N5/10 ; C12N15/12 ; C12P21/02 ; C12P21/08 ; C12Q1/00 ; C12Q1/68 ; C12R1/91
摘要:
HNHCI32 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HNHCI32 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.
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