Invention Grant
- Patent Title: Method for diagnosing an increased risk for thrombosis or a genetic defect causing thrombosis and kit for use with the same
-
Application No.: US804196Application Date: 1997-02-21
-
Publication No.: US5874256APublication Date: 1999-02-23
- Inventor: Rogier Maria Bertina , Pieter Hendrik Reitsma
- Applicant: Rogier Maria Bertina , Pieter Hendrik Reitsma
- Applicant Address: NLX Leiden
- Assignee: Rijks Universiteit Leiden
- Current Assignee: Rijks Universiteit Leiden
- Current Assignee Address: NLX Leiden
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/86 ; C12P21/04 ; C07K16/00 ; G01N33/53
Abstract:
Method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C (APC). The method is directed at detecting one or more mutations at one or more of the cleavage and/or binding sites for APC of Factor V and/or Factor Va or at Factor VIII and/or Factor VIIIa at either nucleic acid or protein level or both.
Public/Granted literature
- US4689522A Flat-panel, full-color, electroluminescent display Public/Granted day:1987-08-25
Information query
