发明授权
US5876949A Antibodies specific for fragile X related proteins and method of using
the same
失效
针对脆性X相关蛋白的特异性抗体及其使用方法
- 专利标题： Antibodies specific for fragile X related proteins and method of using the same
- 专利标题（中）： 针对脆性X相关蛋白的特异性抗体及其使用方法
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申请号： US455073申请日： 1995-05-31
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公开(公告)号： US5876949A公开(公告)日： 1999-03-02
- 发明人: Gideon Dreyfuss , Mikiko C. Siomi , Yan Zhang
- 申请人： Gideon Dreyfuss , Mikiko C. Siomi , Yan Zhang
- 申请人地址： PA Philadelphia
- 专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人地址： PA Philadelphia
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; C07K16/18 ; C12Q1/68 ; G01N33/567 ; C07K16/28 ; C12P21/08
摘要：
The present invention relates to substantially pure FXR1 and FXR2 proteins and isolated nucleic acid molecules encoding the same. Recombinant expression vectors comprising nucleic acid sequences that encode FXR1 and FXR2 protein are also provided. Antibodies which bind to an epitope of FXR1 or FXR2, or FMR1 protein are also provided. The present invention also relates to methods of screening individuals for FMR1 deficiency using antibodies or nucleic acid molecules of the invention and pharmaceutical kits for accomplishing the same.
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