发明授权
- 专利标题： Thrombin inhibitor from the saliva of protostomia
- 专利标题（中）： 凝血酶抑制剂来自原肠the唾液
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申请号： US448438申请日： 1995-08-24
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公开(公告)号： US5876971A公开(公告)日： 1999-03-02
- 发明人: Christiane Noeske-Jungblut , Wolf-Dieter Schleuning , Alejandro Alagon , Lourival Possani , Delia Cuevas-Aguierre , Peter Donner , Bernard Haendler , Ulrike Hechler
- 申请人： Christiane Noeske-Jungblut , Wolf-Dieter Schleuning , Alejandro Alagon , Lourival Possani , Delia Cuevas-Aguierre , Peter Donner , Bernard Haendler , Ulrike Hechler
- 申请人地址： DEX
- 专利权人： Schering Aktiengesellschaft
- 当前专利权人： Schering Aktiengesellschaft
- 当前专利权人地址： DEX
- 优先权： DEX4241659.0 19921204; DEX4304731.9 19930212; DEX4328336.5 19930817; DEX4340798.6 19931125
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K35/12 ; A61K35/56 ; A61K35/64 ; A61K38/00 ; A61K38/55 ; A61K38/57 ; A61P7/02 ; A61P9/10 ; C07H21/04 ; C07K1/14 ; C07K14/435 ; C07K14/81 ; C12N1/21 ; C12N5/10 ; C12N9/99 ; C12N15/15 ; C12P21/00 ; C12P21/02 ; A61K38/16 ; C07K1/36
摘要：
The invention relates to a natural protein or a protein that can be synthetically produced, which is a thrombin inhibitor and can be isolated from the saliva of insects which suck the blood of mammals. Preferred is the Triatoma pallidipennis insect. The protein is used for the treatment of thromboses or unstable angina or arteriosclerosis, or for the prevention of a reblockage of vessels after PTCA/PTA or for the prevention of blood clotting in hemodialysis.
公开/授权文献
- US5008164A Hydrogen-absorbing alloy electrode 公开/授权日：1991-04-16
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