发明授权
- 专利标题: Peptide compounds
- 专利标题(中): 肽化合物
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申请号: US374560申请日: 1995-03-13
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公开(公告)号: US5882645A公开(公告)日: 1999-03-16
- 发明人: Istvan Toth , William Anthony Gibbons
- 申请人: Istvan Toth , William Anthony Gibbons
- 申请人地址: GBX
- 专利权人: The School of Pharmacy, University of London
- 当前专利权人: The School of Pharmacy, University of London
- 当前专利权人地址: GBX
- 优先权: GBX9215780 19920724
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61K47/48 ; A61K51/08 ; A61K51/12 ; A61P37/04 ; C07K14/00 ; C07K14/09 ; C07K14/295 ; A61K39/385 ; A61K38/00
摘要:
Synthetic peptides are widely used to generate antibodies. To induce high antibody response, it is known to conjugate the peptide to a carrier protein (e.g. KLH, BSA) or to incorporate it into polylysine to form a multiple antigenic peptide. Anchors may be built in which are based on fatty acids. According to the invention there is provided a novel lipidic amino acid based anchor system which can maximally enhance the antigenicity of a short synthetic peptide. These novel compounds are entirely peptide-based and may therefore be produced automatically by some step wise peptide synthesis, preferably solid phase step wise peptide synthesis. According to the invention there is also provided such a process.
公开/授权文献
- US4427510A Light driven photocatalytic process 公开/授权日:1984-01-24
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