发明授权
US5925734A Isolated Epstein-Barr virus BZLF2 proteins that bind MHC class II
.beta.chains
失效
分离的Epstein-Barr病毒BZLF2蛋白,其结合MHC II类β链
- 专利标题: Isolated Epstein-Barr virus BZLF2 proteins that bind MHC class II .beta.chains
- 专利标题(中): 分离的Epstein-Barr病毒BZLF2蛋白,其结合MHC II类β链
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申请号: US936854申请日: 1997-09-24
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公开(公告)号: US5925734A公开(公告)日: 1999-07-20
- 发明人: Mark Alderson , Richard J. Armitage , Jeffrey I. Cohen , Michael R. Comeau , Theresa M. Farrah , Lindsey M. Hutt-Fletcher , Melanie K. Spriggs
- 申请人: Mark Alderson , Richard J. Armitage , Jeffrey I. Cohen , Michael R. Comeau , Theresa M. Farrah , Lindsey M. Hutt-Fletcher , Melanie K. Spriggs
- 申请人地址: WA Seattle
- 专利权人: Immunex Corporation
- 当前专利权人: Immunex Corporation
- 当前专利权人地址: WA Seattle
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K39/00 ; C07K14/05 ; C07K16/00 ; C07K16/08 ; C07K1/00 ; C07K14/00 ; C12P21/08
摘要:
Isolated viral proteins, and pharmaceutical compositions made therefrom, are disclosed which are capable of binding to a .beta. chain of a Class II Major Histocompatibility Complex antigen, thereby functioning to inhibit an antigen-specific response. The viral proteins also have superantigen-like activity, and inhibit EBV infection.
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