- 专利标题： Selective .beta.3 adrenergic agonists
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申请号： US882503申请日： 1997-06-25
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公开(公告)号： US5939443A公开(公告)日： 1999-08-17
- 发明人: Michael Gregory Bell , Thomas Alan Crowell , Christine Ann Droste , Donald Paul Matthews , John Hampton McDonald, III , Christopher John Rito , Anthony John Shuker , Mark Alan Winter
- 申请人： Michael Gregory Bell , Thomas Alan Crowell , Christine Ann Droste , Donald Paul Matthews , John Hampton McDonald, III , Christopher John Rito , Anthony John Shuker , Mark Alan Winter
- 申请人地址： IN Indianapolis
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： IN Indianapolis
- 主分类号： A61K31/00
- IPC分类号： A61K31/00 ; A61K31/40 ; A61K31/403 ; A61K31/404 ; A61K31/41 ; A61K31/415 ; A61K31/4164 ; A61K31/4184 ; A61K31/4192 ; A61K31/42 ; A61K31/423 ; A61K31/433 ; A61K31/44 ; A61K31/4427 ; A61K31/4433 ; A61K31/4439 ; A61K31/496 ; A61K31/50 ; A61K31/501 ; A61K31/53 ; A61K31/535 ; A61K31/5355 ; A61K31/537 ; A61K31/5375 ; A61K31/5377 ; A61P3/00 ; A61P3/10 ; A61P43/00 ; C07C235/46 ; C07C255/54 ; C07D209/08 ; C07D213/63 ; C07D235/06 ; C07D235/08 ; C07D235/26 ; C07D249/18 ; C07D257/04 ; C07D263/56 ; C07D263/58 ; C07D285/14 ; C07D295/18 ; C07D333/34 ; C07D401/12 ; C07D403/12 ; C07D409/12 ; C07D413/12 ; C07D417/12
摘要：
The present invention is in the field of medicine, particularly in the treatment of Type II diabetes and obesity. More specifically, the present invention relates to selective .beta.3 adrenergic receptor agonists useful in the treatment of Type II diabetes and obesity. The invention provides compounds and method of treating type II diabetes, comprising administering to a mammal in need thereof compounds of the Formula II: ##STR1## The variables in Formula II are defined herein.
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