发明授权
- 专利标题： Nucleic acid-containing composition, preparation and use thereof
- 专利标题（中）： 含有核酸的组合物，其制备和用途
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申请号： US894339申请日： 1997-08-15
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公开(公告)号： US5945400A公开(公告)日： 1999-08-31
- 发明人: Daniel Scherman , Gerardo Byk , Bertrand Schwartz
- 申请人： Daniel Scherman , Gerardo Byk , Bertrand Schwartz
- 申请人地址： FRX Anthony Cedex
- 专利权人： Rhone-Poulenc Rorer SA
- 当前专利权人： Rhone-Poulenc Rorer SA
- 当前专利权人地址： FRX Anthony Cedex
- 优先权： FRX95/01865 19950217
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K9/127 ; A61K31/785 ; A61K38/00 ; A61K39/395 ; A61K47/34 ; A61K48/00 ; C08L83/06 ; C12N15/87 ; A61K38/10 ; A61K38/08 ; C07K7/00 ; C07K9/00
摘要：
Pharmaceutical composition useful for transfecting a nucleic acid and characterised in that it contains, in addition to the nucleic acid, at least one transfecting agent and a compound causing the condensation of the nucleic acid, wherein the compound is totally or partly derived from a histone, a nucleoline, a protamine and/or a derivative thereof. The use of the composition for transferring nucleic acids in vitro, ex vivo and/or in vivo is also described.
公开/授权文献
- US5260885A Solar power operated computer 公开/授权日：1993-11-09