发明授权
- 专利标题： Rse receptor activation
- 专利标题（中）： Rse受体激活
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申请号： US438864申请日： 1995-05-10
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公开(公告)号： US5955420A公开(公告)日： 1999-09-21
- 发明人: Jian Chen , R. Glenn Hammonds , Paul J. Godowski , Melanie R. Mark , Jennie P. Mather , Ronghao Li
- 申请人： Jian Chen , R. Glenn Hammonds , Paul J. Godowski , Melanie R. Mark , Jennie P. Mather , Ronghao Li
- 申请人地址： CA So. San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： CA So. San Francisco
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/745 ; C12N1/21 ; C12N15/12 ; A61K38/18 ; C07K14/475
摘要：
An activator of the Rse receptor protein tyrosine kinase has been identified which is encoded by growth arrest-specific gene 6 (gas6). Accordingly, the present invention provides a method of activating the Rse receptor by exposing a cell comprising the Rse receptor to exogenous gas6 polypeptide. Moreover, the present invention is directed to a method for enhancing the survival, proliferation or differentiation of a cell comprising a Rse receptor by exposing the cell to exogenous gas6 polypeptide. The types of cells which can be treated according to the method include glial cells such as Schwann cells.
公开/授权文献
- US5009023A High speed fishing lure 公开/授权日：1991-04-23
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