发明授权
- 专利标题: Antisense inhibition of cellular inhibitor of apoptosis-1 expression
- 专利标题(中): 反义抑制细胞凋亡抑制因子-1表达
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申请号: US205204申请日: 1998-12-03
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公开(公告)号: US5958772A公开(公告)日: 1999-09-28
- 发明人: C. Frank Bennett , Elizabeth J. Ackermann , Lex M. Cowsert
- 申请人: C. Frank Bennett , Elizabeth J. Ackermann , Lex M. Cowsert
- 申请人地址: CA Carlsbad
- 专利权人: Isis Pharmaceuticals Inc.
- 当前专利权人: Isis Pharmaceuticals Inc.
- 当前专利权人地址: CA Carlsbad
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K31/7115 ; A61K31/712 ; A61K31/7125 ; A61K38/00 ; A61K48/00 ; A61P29/00 ; A61P31/00 ; A61P35/00 ; A61P37/02 ; A61P43/00 ; C12N15/113 ; C12Q1/68 ; C07H21/04 ; C12N15/00
摘要:
Antisense compounds, compositions and methods are provided for modulating the expression of Cellular Inhibitor of Apoptosis-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Cellular Inhibitor of Apoptosis-1. Methods of using these compounds for modulation of Cellular Inhibitor of Apoptosis-1 expression and for treatment of diseases associated with expression of Cellular Inhibitor of Apoptosis-1 are provided.
公开/授权文献
- US5441173A Piston depositor 公开/授权日:1995-08-15
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