- 专利标题： Efficient method for the conversion of nitriles to amidines
-
申请号： US166722申请日： 1998-10-05
-
公开(公告)号： US5962693A公开(公告)日： 1999-10-05
- 发明人: Philip Ma , Pasquale N. Confalone , Hui-Yin Li
- 申请人： Philip Ma , Pasquale N. Confalone , Hui-Yin Li
- 申请人地址： DE Wilmington
- 专利权人： DuPont Pharmaceuticals Company
- 当前专利权人： DuPont Pharmaceuticals Company
- 当前专利权人地址： DE Wilmington
- 主分类号： A61K31/42
- IPC分类号： A61K31/42 ; A61K31/4245 ; A61P7/02 ; C07D261/04 ; C07D413/10 ; C07F9/653 ; C07D261/02 ; C07C257/18 ; C07D261/08
摘要：
The present invention relates to processes for the conversion of nitrites to amidines in the preparation of compounds which are antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex. The compounds described herein are potent thrombolytics and useful for the inhibition of platelet aggregation in the treatment of thromboembolic disorders.
公开/授权文献
- US4799166A Apparatus for automatically analyzing gases in oil 公开/授权日：1989-01-17