发明授权
- 专利标题： Diagnosis of metastatic cancer by the mts-1 gene
- 专利标题（中）： 通过mts-1基因诊断转移性癌症
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申请号： US468942申请日： 1995-06-06
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公开(公告)号： US5965360A公开(公告)日： 1999-10-12
- 发明人: Sayeeda Zain , Eugene Lukanidin
- 申请人： Sayeeda Zain , Eugene Lukanidin
- 申请人地址： AZ Tucson
- 专利权人： Research Corporation Technologies, Inc.
- 当前专利权人： Research Corporation Technologies, Inc.
- 当前专利权人地址： AZ Tucson
- 主分类号： G01N33/574
- IPC分类号： G01N33/574 ; A61K38/00 ; A61K39/395 ; A61K48/00 ; A61P35/00 ; C07H21/04 ; C07K14/47 ; C07K16/18 ; C12N1/21 ; C12N5/00 ; C12N5/10 ; C12N15/09 ; C12N15/12 ; C12R1/19 ; C12R1/91 ; C12Q1/68
摘要：
The present invention is directed towards the diagnosis of malignant cancer by detection of the mts-1 mRNA or the mts-1 protein, encoded by the mts-1 gene. The present invention contemplates the use of recombinant mts-1 DNA and antibodies directed against the mts-1 protein to diagnose the metastatic potential of several types of tumor cells, including, for example, thyroid, epithelial, lung, liver and kidney tumor cells. The present invention is also directed to mammalian cell lines and tumors with high and low metastatic potential which have been developed to serve as useful model systems for in vitro and in vivo anti-metastasis drug screening.
公开/授权文献
- US5139882A Aqueous polyacrylate systems for varnishing plastic surfaces 公开/授权日：1992-08-18
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