- 专利标题： Peptide/protein suspending formulations
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申请号： US238159申请日： 1999-01-28
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公开(公告)号： US5972370A公开(公告)日： 1999-10-26
- 发明人: James B. Eckenhoff, deceased , Leslie A. Holladay , John Joseph Leonard, Jr. , Iris K. M. Leung , Sally A. Tao , Judy A. Magruder , John P. Carr , Jeremy C. Wright
- 申请人： James B. Eckenhoff, deceased , Leslie A. Holladay , John Joseph Leonard, Jr. , Iris K. M. Leung , Sally A. Tao , Judy A. Magruder , John P. Carr , Jeremy C. Wright
- 申请人地址： CA Palo Alto
- 专利权人： Alza Corporation
- 当前专利权人： Alza Corporation
- 当前专利权人地址： CA Palo Alto
- 主分类号： A61K9/10
- IPC分类号： A61K9/10 ; A61K9/00 ; A61K38/21 ; A61K47/10 ; A61K47/32 ; A61K47/38 ; A61F2/00 ; A61K9/14 ; A61K38/00 ; C07K17/02
摘要：
The present invention provides improved compositions for improving the chemical and physical stability of peptides and proteins. The invention provides a liquid beneficial agent formulation containing a liquid suspension comprising at least 5% by weight beneficial agent and having a viscosity and beneficial agent size which minimizes settling of the agent in suspension over the extended delivery period.
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