发明授权
- 专利标题： Aminostilbazole derivative and medicine
- 专利标题（中）： 氨基芪衍生物和药物
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申请号： US765131申请日： 1996-10-02
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公开(公告)号： US5972976A公开(公告)日： 1999-10-26
- 发明人: Hiroyoshi Hidaka , Akira Matsuura , Masato Matsuda
- 申请人： Hiroyoshi Hidaka , Akira Matsuura , Masato Matsuda
- 专利权人： Nippon Shinyaku Company, Limited
- 当前专利权人： Nippon Shinyaku Company, Limited
- 优先权： JPX6-068252 19940406
- 主分类号： C07D213/74
- IPC分类号： C07D213/74 ; A61K9/20 ; A61K31/44 ; A61K31/4427 ; A61K31/53 ; A61P35/00 ; C07D213/42 ; C07D213/76 ; C07D213/89 ; C07D239/26 ; C07D239/28 ; C07D241/12 ; C07D241/14 ; C07D401/06 ; C07D405/06 ; C07D413/00 ; C07D211/72 ; C07D213/36 ; C07D241/02
摘要：
The invention relates to an aminostilbazole derivative of the following formula or a hydrate thereof, and a salt thereof. ##STR1## wherein R.sup.1 and R.sup.2 each represents hydrogen etc.; R.sup.3, R.sup.4, R.sup.13, and R.sup.14 each represents hydrogen, C.sub.1-3 acyl, halogen, hydroxy etc.; R.sup.5 represents hydrogen or hydroxy-substituted C.sub.1-3 alkyl etc.; R.sup.6 represents benzenesulfonyl substituted by C.sub.1-3 alkoxy etc.; ring Y represents phenyl etc.; ring Z represents 4-pyridyl, its oxide etc. The compound is useful or the treatment of various malignant tumors.
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